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Invitrogen™ IRAK-M Polyclonal Antibody

Product Code. 12828182
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12828182 100 μg 100µg
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Product Code. 12828182 Supplier Invitrogen™ Supplier No. PA519969

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Description

Rabbit Polyclonal Antibody

In Western blot applications, this antibody detects a band at ~68kDa. A suggested positive control is mouse spleen tissue lysate. PA5-19969 can be used with blocking peptide PEP-0094.

IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRAK-M
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene IRAK3
Gene Accession No. Q8K4B2, Q9Y616
Gene Alias 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
Gene Symbols IRAK3
Host Species Rabbit
Immunogen A peptide corresponding to 16 amino acids from the carboxy terminus of human IRAK-M.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11213, 314870, 73914
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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