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IOX1, MedChemExpress

Product Code. 16491317
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Quantity:
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10 mg
50 mg
Unit Size:
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50mg
5mg
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Product Code. 16491317

Brand: Medchem Express HY12304

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Description

MedChemExpress IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively. IOX1 also inhibits ALKBH5.

IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively. IOX1 also inhibits ALKBH5.

Specifications

Chemical Name or Material IOX1
CAS 5852-78-8
Color Off-White
Purity Grade Notes Research
Molecular Formula C10H7NO3
Quantity 50 mg
Solubility Information DMSO : 13.33 mg/mL (70.47 mM; Need ultrasonic and warming)
SMILES O=C(C1=C2C=CC=NC2=C(O)C=C1)O
Molecular Weight (g/mol) 189.17
Formula Weight 189.17
Percent Purity 98.38%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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