2-Iodoacetamide, 98%, stab. with ca 5-8% water


Overview
Brand: Alfa Aesar

Manufacturer Part Number: A14715.06

UNSPSC: 12352106

Code: NEW

Additional Details:
Additional Details: CAS Number: 144-48-9 Weight: 0.01000kg


Quantity 5g

Product Code. 11467736

Quantity Price
1 £ 14.2 / 5g
Estimated Shipment date
from Supplier 13-04-2017
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Description and Specification

Chemical Identifiers

Chemical Name or Material Iodoacetamide
CAS 144-48-9
Name Note stabilized with ≈5 to 8% water
Molecular Formula ICH2CONH2
Formula Weight 184.96
MDL Number MFCD00008028
UN Number UN2811
Beilstein 1739080

Specification

Health Hazard 2 GHS H Statement
H301-H315-H319-H317-H335
Health Hazard 3 GHS P Statement
P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P363-P405-P501a
Formula Weight 184.96
Quantity 5g
RTECS Number AC4200000
UN Number UN2811
Health Hazard 1 Danger
Assay 98%
TSCA TSCA
Name Note stabilized with ≈5 to 8% water
MDL Number MFCD00008028
Beilstein 1739080
Recommended Storage 2° to 8°C
DOT Information Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
Molecular Formula ICH2CONH2
Chemical Name or Material Iodoacetamide
Assay Percent Range 98%, stabilized with ca 5% water
CAS 144-48-9

Applications
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Solubility
Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.

Notes
Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.

Documentation

Technical documents

Safety and Handling

Danger

GHS H Statement
H301-H315-H319-H317-H335

GHS P Statement
P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P363-P405-P501a

2° to 8°C