Integrin beta 7 Antibody (FIB504), PE, Novus Biologicals™

Rabbit Monoclonal Antibody

Brand:  Novus Biologicals NBP2-81086PE

Product Code. 18253419

Description

Integrin beta 7 Monoclonal specifically detects Integrin beta 7 in Human, Mouse samples. It is validated for Flow Cytometry.

Specifications

• Antigen: Integrin beta 7
• Classification: Monoclonal
• Conjugate: PE
• Formulation: PBS
• Gene Symbols: ITGB7
• Immunogen: FIB504 was prepared by immunizing rats with TK1 cells.
• Quantity: 0.1 mL
• Research Discipline: Signal Transduction
• Gene ID (Entrez): 3695
• Target Species: Human, Mouse
• Form: Purified

• Applications: Flow Cytometry
• Clone: FIB504
• Dilution: Flow Cytometry
• Gene Alias: Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
• Host Species: Rabbit
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: FIB504 recognizes an epitope on Integrin beta 7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG κ