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Integrin beta 7 Antibody (FIB504), Alexa Fluor™ 532, Novus Biologicals™

Product Code. 18352321 Shop All Bio Techne Products
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0.1 mL
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0.10mL
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Product Code. 18352321 Supplier Novus Biologicals Supplier No. NBP281086AF532

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Rabbit Monoclonal Antibody

Integrin beta 7 Monoclonal specifically detects Integrin beta 7 in Human, Mouse samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Integrin beta 7
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone FIB504
Conjugate Alexa Fluor 532
Dilution Flow Cytometry, Immunocytochemistry/Immunofluorescence
Formulation 50mM Sodium Borate
Gene Alias Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
Gene Symbols ITGB7
Host Species Rabbit
Immunogen FIB504 was prepared by immunizing rats with TK1 cells.
Purification Method Protein A purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 3695
Test Specificity FIB504 recognizes an epitope on Integrin beta 7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
Target Species Human, Mouse
Content And Storage Store at 4°C in the dark.
Form Purified
Isotype IgG κ
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