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Integrin alpha 4 beta 7 (LPAM-1) Rat anti-Mouse, APC, Clone: DATK32 (DATK-32), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-5887-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15360770

  • £155.16 / 100µg


EU Stock 9
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Disclaimers:

For Research Use Only.


Specifications

Description

The DATK32 monoclonal antibody binds to a combinatorial epitope of mouse LPAM-1 (alpha 4/ beta 7), which is a heterodimer of the the 154kDa alpha 4 subunit and the 130kDa beta 7 subunit. In mouse, the beta 7 subunit is found on the majority of mature lymphocytes and a small population of thymocytes and bone marrow cells. LPAM-1 is an integrin involved in the transendothelial migration of lymphocytes across high endothelial venules (HEV), and is know to bind several ligands including MAdCAM-1, VCAM-1 and fibronectin. Binding of the DATK32 monoclonal antibody has been shown to induce aggregation of the CD8+ T cell lymphoma TK1, and block LPAM-1-mediated cell adhesion.
Description & Specifications

Specifications

Integrin alpha 4 beta 7 (LPAM-1)
DATK32 (DATK-32)
Allophycocyanin
Conjugated
IgG2a
RUO
Primary
Murine
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal