Integrin alpha 2b/CD41 Antibody (PM6/248), DyLight 680, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NB100-63779FR

Product Code. 18087345

Description

Integrin alpha 2b/CD41 Monoclonal specifically detects Integrin alpha 2b/CD41 in Human, Mustelid, Baboon samples. It is validated for Flow Cytometry.

Specifications

• Antigen: Integrin alpha 2b/CD41
• Classification: Monoclonal
• Conjugate: DyLight 680
• Gene Accession No.: P08514
• Gene Symbols: ITGA2B
• Immunogen: Human platelet plasma membrane
• Quantity: 0.1 mL
• Research Discipline: Angiogenesis, Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Extracellular Matrix, Immunology, Signal Transduction, Stem Cell Markers
• Gene ID (Entrez): 3674
• Target Species: Human, Mustelid, Baboon
• Form: Purified

• Applications: Flow Cytometry
• Clone: PM6/248
• Dilution: Flow Cytometry
• Gene Alias: CD41, CD41 antigen, CD41BHPA3, GP2Bintegrin alpha-IIb, GPalpha IIb, GPIIb, GTA, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41), integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B), ITGAB, platelet fibrinogen receptor, alpha subunit, Platelet membrane glycoprotein IIb, platelet-specific antigen BAK
• Host Species: Mouse
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: NB100-63779 recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1

For Research Use Only