Invitrogen™ INSIG2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA576887

Product Code. 15837716

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Specifications

• Antigen: INSIG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INSIG2
• Gene Alias: 2900053I11Rik; C730043J18Rik; Insig2; INSIG-2; INSIG2 membrane protein; INSIG-2 membrane protein; insulin induced factor 2; insulin induced gene 2; insulin induced protein 2; insulin-induced 2 protein; insulin-induced gene 2 protein; insulin-induced membrane protein 2; MGC26273
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51141, 72999
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 1% BSA, 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q91WG1, Q9Y5U4
• Gene Symbols: INSIG2
• Immunogen: KLH conjugated synthetic peptide derived from human Insig2: 65-160.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG