Inhibin beta B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16837504	Proteintech 17577-1-AP-20UL	20 μL
16827504	Proteintech 17577-1-AP-150UL	150 μL

Description

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Specifications

• Antigen: Inhibin beta B
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Rat, Mouse
• Gene Accession No.: P09529, P17491, Q04999
• Gene ID (Entrez): 16324, 25196, 3625
• Immunogen: Inhibin beta B Fusion Protein Ag10956
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: INHBB

• Concentration: 0.23 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Activin beta B chain, INHBB, Inhibin beta B chain, inhibin, beta B
• Gene Symbols: INHBB
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody