Invitrogen™ INHBC Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA536525

Product Code. 15553911

Description

This antibody detects endogenous protein at a molecular weight of 30 kDa. Purity is >95% by SDS-PAGE.

Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth depending on their subunit composition. Activins oppose the funtions of inhibins. Inhibins are predominantly expressed in liver, uterus and ovary tissue, but also in benign prostatic hyperplasia. Inhibin A, a dimer of alpha and beta-A, and inhibin B, a dimer of alpha and beta-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin beta-C forms a homodimer and its expression is predominant in adult liver and in benign prostatic hyperplasia.

Specifications

• Antigen: INHBC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INHBC
• Gene Alias: activin beta-C chain; activin/inhibin beta C; IHBC; Inhbc; inhibin beta C; inhibin beta C chain; inhibin beta C subunit; inhibin beta-C; inhibin, beta C
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3626
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P55103
• Gene Symbols: INHBC
• Immunogen: Synthetic peptide corresponding to amino acids 100-150 of human Inhibin beta-C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG