Invitrogen™ INHBC Monoclonal Antibody (CL6916)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA531444

Product Code. 16394884

Description

Immunogen sequence: TPRAGGQCPA CGGPTLELES QRELLLDLAK RSILDKLHLT QRPTLNRPVS RAALRTALQH LHGVPQGALL EDNREQECEI Highest antigen sequence indentity to the following orthologs: Mouse - 65%, Rat - 63%.

Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth depending on their subunit composition. Activins oppose the funtions of inhibins. Inhibins are predominantly expressed in liver, uterus and ovary tissue, but also in benign prostatic hyperplasia. Inhibin A, a dimer of alpha and beta-A, and inhibin B, a dimer of alpha and beta-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin beta-C forms a homodimer and its expression is predominant in adult liver and in benign prostatic hyperplasia.

Specifications

• Antigen: INHBC
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P55103
• Gene Symbols: INHBC
• Immunogen: Recombinant protein fragment of Human INHBC (Product #RP-108706)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: CL6916
• Conjugate: Unconjugated
• Gene: INHBC
• Gene Alias: activin beta-C chain; activin/inhibin beta C; IHBC; Inhbc; inhibin beta C; inhibin beta C chain; inhibin beta C subunit; inhibin beta-C; inhibin, beta C
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3626
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid