INHA Monoclonal Antibody (4A2), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515315

Product Code. 11345293

Description

MA5-15315 targets INHA (Inhibin alpha) in indirect ELISA, IF and IHC applications and shows reactivity with Human samples. The MA5-15315 immunogen is purified recombinant fragment of human INHA expressed in E. Coli. MA5-15315 detects INHA (Inhibin alpha) which has a predicted molecular weight of approximately 40kDa.

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

Specifications

• Antigen: INHA
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.03% sodium azide
• Gene Accession No.: P05111
• Gene Symbols: INHA
• Immunogen: Purified recombinant fragment of human INHA expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunocytochemistry, Immunohistochemistry
• Clone: 4A2
• Conjugate: Unconjugated
• Gene: INHA
• Gene Alias: A inhibin subunit; A-inhibin subunit; AW555078; IHA; Inha; inhibin; inhibin alpha; inhibin alpha chain; inhibin alpha subunit
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3623
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid