ING3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16875724	Proteintech 16187-1-AP-20UL	20 μL
16865724	Proteintech 16187-1-AP-150UL	150 μL

Description

This antibody is specifically against p47ING3.

The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

Specifications

• Antigen: ING3
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse, Human
• Gene Accession No.: Q498T3, Q8VEK6, Q9NXR8
• Gene ID (Entrez): 312154, 54556, 71777
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ING3

• Concentration: 0.14 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Eaf4, ING2, ING3, Inhibitor of growth protein 3, p47ING3
• Gene Symbols: Ing3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody