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Invitrogen™ ING1 Polyclonal Antibody
Description
In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) ING2 and less than 1% cross-reactivity with with rhING3, rhING4, and rhING5 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Specifications
Specifications
| Antigen | ING1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 5% trehalose and No Preservative |
| Gene | ING1 |
| Gene Accession No. | Q9UK53 |
| Gene Alias | 2610028J21Rik; AA407184; AI875420; growth inhibitor ING1; growth inhibitory protein ING1; ING1; inhibitor of growth family member 1; inhibitor of growth family, member 1; inhibitor of growth protein 1; mING1h; p24ING1c; p33; p33ING; p33ING1; p33ING1b; p33ING1c; p37Ing1b; p47; p47ING1a; tumor suppressor ING1 |
| Gene Symbols | ING1 |
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