Invitrogen™ Influenza A NP Recombinant Rabbit Monoclonal Antibody (061)

Rabbit Recombinant Monoclonal Antibody

Produktcode	Marke	Quantity
30533783	Invitrogen™ MA560361	100 μg
30533780	Invitrogen™ MA560362	20 μg

Beschreibung

Widely recognize Influenza A Nucleoprotein. Has cross-reactivity in ELISA and WB with: H1N1 (A/Brevig Mission/1/1918) NP; H1N1 (A/Brisbane/02/2018) NP; H1N1 (A/California/07/2009) NP; H1N1 (A/Guangdong-Maonan/SWL1536/2019) NP; H1N1 (A/Hawaii/70/2019) NP; H1N1 (A/Michigan/45/2015 NP; H1N1 (A/Puerto Rico/8/34/Mount Sinai) NP (I116M); H1N1 (A/Victoria/2570/2019)/(A/Wisconsin/588/2019) NP; H2N2 (A/Ann Arbor/6/1960) NP; H3N2 (A/Aichi/2/1968) NP; H3N2 (A/Cambodia/e0826360/2020 (H3N2)-like NP; H3N2 (A/Darwin/9/2021)/(A/Darwin/6/2021) NP Protein; H3N2 (A/Hong Kong/1/1968) NP; H3N2 (A/Hong Kong/2671/2019) NP; H3N2 (A/Hong Kong/45/2019) NP; H3N2 (A/Hong Kong/4801/2014) NP; H3N2 (A/Kansas/14/2017) NP; H3N2 (A/Switzerland/9715293/2013) NP; H5N1 (A/Texas/37/2024) NP Protein; H7N9 (A/Anhui/1-BALF_RG6/2013) NP; H7N9 (A/Shanghai/2/2013) NP. Has cross-reactivity in ELISA with: H1N1 (A/Victoria/2454/2019) NP; No cross-reactivity in ELISA and WB with: Influenza B (B/Austria/1359417/2021) NP Protein; Influenza B (B/Brisbane/60/2008) NP; Influenza B (B/Colorado/06/2017) NP; Influenza B (B/Florida/4/2006) NP; Influenza B (B/Phuket/3073/2013) NP; Influenza B (B/Washington/02/2019) NP; No cross-reactivity in ELISA with: SARS-CoV-2 Nucleocapsid Protein; HCoV-229E Nucleocapsid Protein HCoV-NL63 Nucleocapsid Protein; HCoV-HKU1 Nucleocapsid Protein; HCoV-OC43 Nucleocapsid Protein.

The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. 'NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56' (Portela et al 2002).

Spezifikation

• Antigen: Influenza A NP
• Concentration: 1 mg/mL
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with no preservative
• Immunogen: Recombinant Influenza A H3N2 (A/Hong Kong/1/1968) Nucleoprotein/NP protein (Met1-Asn498).
• Product Type: Antibody

• Clone: 061
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Virus
• Gene Alias: Influenza nucleoprotein
• Primary or Secondary: Primary
• Purification Method: Protein A