Invitrogen™ Influenza A H1N1 HA (Swine Flu 2009) Recombinant Rabbit Monoclonal Antibody (376)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30536169	Invitrogen™ MA560306	100 μL
30534791	Invitrogen™ MA560307	20 μL

Description

Recognizes H1N1 (A/California/04/2009) HA; H1N1 (A/California/07/2009) HA. Has cross-reactivity in ELISA with: H1N1 (A/Solomon Islands/3/2006) HA; H1N1 (A/Ohio/UR06-0091/2007) HA; H1N1 (A/New Caledonia/20/1999) HA; H1N1 (A/Puerto Rico/8/1934) HA; H1N1 (A/WSN/1933) HA; H1N2 (A/swine/Guangxi/13/2006) HA; H1N3 (A/duck/NZL/160/1976) HA; H5N1 (A/Viet Nam/1203/2004) HA; H5N1 (A/turkey/Turkey/1/2005) HA; H5N1 (A/Anhui/1/2005) HA2 Sub-unit; No cross-reactivity in ELISA with: H1N1 (A/California/04/2009) HA1 Sub-unit; H1N1 (A/Brevig Mission/1/1918) HA; H1N1 (A/Brisbane/59/2007) HA; H5N1 (A/Indonesia/5/2005) HA; H5N1 (A/Anhui/1/2005) HA; H3N2 (A/Brisbane/10/2007) HA; H5N1 (A/bar-headed goose/Qinghai/14/2008) HA; Influenza B (B/Florida/4/2006) HA.

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.

Specifications

• Antigen: Influenza A H1N1 HA (Swine Flu 2009)
• Concentration: 1 mg/mL
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 10% trehalose and no preservative
• Immunogen: Recombinant H1N1 HA protein.
• Product Type: Antibody

• Clone: 376
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Virus
• Gene Alias: flu hemagglutinin; H1N1 HA; H1N1 hemagglutinin; Influenza H1N1; influenza hemagglutinin
• Primary or Secondary: Primary
• Purification Method: Protein A