Influenza A H1N1 HA Monoclonal Antibody (C102 (IV.C102)), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA183250

Product Code. 11594623

Description

This antibody is specific for the haemagglutinin of the Influenza A H1N1 serotype and does not react with H2N2, H3N2, Influenza B, RSV, Parainfluenza I, II or III, Adenovirus, mumps or measle antigens. Mouse anti Influenza A heamagglutinin antibody, clone C102 recognizes the haemagglutinin of the Influenza A H1N1 serotype and does not react with H2N2, H3N2, Influenza B, RSV, Parainfluenza I, II or III, Adenovirus, mumps or measle antigens.

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.

Specifications

• Antigen: Influenza A H1N1 HA
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with <0.1% sodium azide; pH 7.2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Frozen)
• Clone: C102 (IV.C102)
• Conjugate: Unconjugated
• Gene Alias: flu hemagglutinin; H1N1 HA; H1N1 hemagglutinin; Influenza H1N1; influenza hemagglutinin
• Immunogen: Influenza A/USSR/90/77.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid