Invitrogen™ Infliximab Chimeric Recombinant Human Monoclonal Antibody (cA2 (Infliximab))

Human Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA547798

Product Code. 17950871

Description

Specificity: Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.

Infliximab with the brand name of Remicade, is a chimeric monoclonal IgG1 antibody. It binds to TNF-alpha, which is a key proinflammatory cytokine involved in chronic inflammatory diseases. Infliximab functions as TNF-alpha blocker to disrupt the interaction of TNF-alpha with its receptors.

Specifications

• Antigen: Infliximab Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P08183
• Host Species: Human
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5243
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Functional Assay, Western Blot
• Clone: cA2 (Infliximab)
• Conjugate: Unconjugated
• Gene: ABCB1
• Gene Alias: Remicade; TA-650
• Immunogen: Purified recombinant human TNF (rTNF).
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ