Indomethacin, 98%


Overview
Brand: Alfa Aesar

Manufacturer Part Number: A19910-06

INDOMETHACIN, 98% 5G

UNSPSC: 12352005

Code: NEW

Additional Details:
Additional Details: CAS Number: 53-86-1 Weight: 0.01000kg Transport: UN number : 2811 Chem class : 1 Pack group : I


Quantity 5g

Product Code. 11496380

Quantity Price
1 £ 19.5 / 5g
Estimated Shipment date
from Supplier 07-12-2016
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Description and Specification

Chemical Identifiers

Chemical Name or Material Indomethacin
CAS 53-86-1
Molecular Formula C19H15NO4
Formula Weight 321.33g/mol
MDL Number MFCD00057095
UN Number UN2811
Beilstein 497341
Merck Index 14,4968

Specification

Quantity 5g
Chemical Name or Material Indomethacin
CAS 53-86-1
Assay 98%
Assay Percent Range 0.98
Molecular Formula C19H15NO4
Formula Weight 321.33g/mol
MDL Number MFCD00057095
UN Number UN2811
Beilstein 497341
Merck Index 14,4968
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H300-H341
Fatal if swallowed.
Suspected of causing genetic defects.
Health Hazard 3 GHS P Statement
P281-P301+P310-P308+P313-P321-P405-P501a
Use personal protective equipment as required.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF exposed or concerned: Get medical advice/attention.
S
DOT Information Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
TSCA TSCA

Applications
It is a non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It finds its application as gout suppressant, non-steroidal anti-inflammatory drug and analgesic. It also plays many biological roles. Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.

Solubility
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.

Notes
Store away from oxidizing agents, strong bases and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Safety and Handling

Danger

GHS H Statement
H300-H341
Fatal if swallowed.
Suspected of causing genetic defects.

GHS P Statement
P281-P301+P310-P308+P313-P321-P405-P501a
Use personal protective equipment as required.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF exposed or concerned: Get medical advice/attention.
S