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Indomethacin, 98%, Thermo Scientific Chemicals

Catalog Number 11496380
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Quantity:
5 g
25 g
100 g
This item is not returnable. View return policy
53-86-1
C19H16ClNO4
357.79
MFCD00057095
CGIGDMFJXJATDK-UHFFFAOYSA-N
indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
3715
CHEBI:49662
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
This item is not returnable. View return policy
53-86-1
C19H16ClNO4
357.79
MFCD00057095
CGIGDMFJXJATDK-UHFFFAOYSA-N
indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
3715
CHEBI:49662
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

It is a non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It finds its application as gout suppressant, non-steroidal anti-inflammatory drug and analgesic. It also plays many biological roles. Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.

Notes
Store away from oxidizing agents, strong bases and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY
Melting Point 158°C to 161°C
Assay Percent Range 0.98
Quantity 5 g
UN Number UN2811
Beilstein 497341
Sensitivity Light sensitive
Merck Index 14,4968
Solubility Information Soluble in acetone (40mg/mL- clear,yellow solution),ethanol (20mg/mL),ether,castor oil; Soluble in chloroform (50mg/mL- clear,yellow,extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Formula Weight 357.8
Percent Purity 98%
Chemical Name or Material Indomethacin
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