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DiscoverX InCELL Hunter™ A549 GLP Methyltransferase Cell Line

Product Code. 17324789
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Quantity:
2 Vials
Unit Size:
2 ampoules
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Product Code. 17324789

Brand: DiscoverX 960045C15

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This item is not returnable. View return policy

Description

The InCELL Hunter™ A549 GLP Methyltransferase Cell Line measures target engagement via compound-induced stabilization of GLP target protein. This cell line ships as two vials of cryopreserved cells.

The InCELL Hunter™ A549 GLP Methyltransferase Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with regulators of epigenetics pathways. This cell line enables assessment of compound-engagement-based stabilization of GLP via detection of GLP levels. This product uses EFC technology. The cell line included overexpresses GLP target protein fused to PL. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Target Engagement
Cell Line A549
For Use With (Application) Cell Lines
Primary Agonist UNC 0638
Quantity 2 Vials
Target Entry GLP
Accession Number NM_024757
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