Invitrogen™ ILK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5119671

Product Code. 17741074

Description

Positive Control: Mouse skeletal muscle tissue, rat lung tissue, A431, MG-63, PANC-1, rat skeletal muscle tissue, human kidney tissue, human pancreas tissue, mouse heart tissue. Subcellular Location: Cell junction, Cell membrane, Cytoplasm.

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: ILK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ILK
• Gene Alias: 59 kDa serine/threonine-protein kinase; AA511515; epididymis secretory protein Li 28; ESTM24; HEL-S-28; ILK; ILK1; ILK-1; ILK2; ILK-2; integrin binding protein kinase; Integrin linked ILK; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; integrin-linked protein kinase; loc; lost-contact; main squeeze; msq; P59; p59ILK; zgc:65842; zilk
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16202, 170922, 3611
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O55222, Q13418, Q99J82
• Gene Symbols: ILK
• Immunogen: Recombinant protein within Human Integrin linked ILK aa 1-290.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG