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Ilginatinib, MedChemExpress

Product Code. 16493777
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Product Code. 16493777 Supplier Medchem Express Supplier No. HY19631A

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Description

MedChemExpress Ilginatinib (NS-018) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM).

Ilginatinib (NS-018) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM).

Specifications

Chemical Name or Material Ilginatinib
CAS 1239358-86-1
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C21H20FN7
Quantity 50 mg
Synonym NS-018
Solubility Information DMSO : 100 mg/mL (256.79 mM; Need ultrasonic)
SMILES CN1N=CC(C2=CC(N[C@H](C3=CC=C(F)C=C3)C)=NC(NC4=NC=CN=C4)=C2)=C1
Molecular Weight (g/mol) 389.43
Formula Weight 389.43
Percent Purity 95.07%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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