Invitrogen™ IL9R alpha Monoclonal Antibody (AH9R7), PE

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA528557

Product Code. 16312824

Description

This antibody recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Recommended dilution is for 100 μL of whole blood or 1x10^6 cells in suspension.

The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: IL9R alpha
• Classification: Monoclonal
• Concentration: 0.055 mg/mL
• Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
• Gene Accession No.: Q01113
• Gene Symbols: IL9R
• Immunogen: Human CD129-transfected cell line.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: AH9R7
• Conjugate: PE
• Gene: IL9R
• Gene Alias: CD129; IL-9 receptor; IL9R; IL-9R; interleukin 9 receptor; interleukin-9 receptor
• Host Species: Mouse
• Purification Method: Size-exclusion chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3581
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid