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Invitrogen™ IL23R Recombinant Rabbit Monoclonal Antibody (K03_1K44)

Description
IL23R Recombinant Monoclonal Antibody for Western Blot
IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.
Specifications
Specifications
| Antigen | IL23R |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K03_1K44 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide |
| Gene | Il23r |
| Gene Accession No. | Q5VWK5, Q8K4B4 |
| Gene Alias | IBD17; IL 23R; IL-23 receptor; IL23R; IL-23R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor |
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Product Title
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