Invitrogen™ IL18R1 Monoclonal Antibody (112624)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA523855

Product Code. 15583542

Description

In direct ELISAs, this antibody does not cross-react with recombinant mouse (rm) IL-1 RI, rmIL-1 RII, rhIL-1 R3, recombinant human (rh) IL-1 R4, rhIL-1 R5, recombinant rat IL-1 R6, rmIL-1 R7, rhIL-1 R8, rhIL-1 R9, or rmSIGIRR. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.

Specifications

• Antigen: IL18R1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q61098
• Gene Symbols: Il18r1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse IL-18 R alpha Ser19-Gly326.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Neutralization, Western Blot
• Clone: 112624
• Conjugate: Unconjugated
• Gene: Il18r1
• Gene Alias: CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; Il18r1; IL-18R1; IL-18R-1; IL18RA; Il18ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin 1 receptor related protein; interleukin 18 receptor 1; Interleukin-18; interleukin-18 receptor 1; Interleukin-18 receptor alpha
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 16182
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized