Invitrogen™ IL17RD Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5111181

Product Code. 17109103

Description

Immunogen sequence: LACKPFWKPR NLNISQHGSD MQVSFDHAPH NFGFRFFYLH YKLKHEGPFK RKTCKQEQTT ETTSCLLQNV SPGDYIIELV DDTNTTRKVM Highest antigen sequence indentity to the following orthologs: Rat - 82%, Mouse - 84%.

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.

Specifications

• Antigen: IL17RD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Il17rd
• Gene Alias: 2810004A10Rik; AI428510; HH18; hSef; IL-17 receptor D; IL17RD; IL-17RD; IL17Rhom; IL17RLM; interleukin 17 receptor D; interleukin-17 receptor D; Interleukin-17 receptor-like protein; mSef; RGD1565237; SEF; sef homolog; Sef-S; UNQ6115/PRO20026
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54756
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NFM7
• Gene Symbols: Il17rd
• Immunogen: Recombinant Protein corresonding to Human IL17RD. Recombinant protein control fragment (Product #RP-96359).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG