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IL10RA Chimeric Recombinant Rabbit Monoclonal Antibody (1B1.3a), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen MA548250

Additional Details : Weight : 0.01000kg

Product Code. 17971611

  • £426.00 / 200µg
Estimated Shipment: 23-08-2024
to see stock.

Description

Description

Specificity: This antibody recognises mouse IL-10R which is a cell surface glycoprotein and a receprot for anti-inflammatory IL-10. The epitope recognised by this antibody has been localised to the ligand binding domain within the extracellular region of mouse IL-10R.

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Specifications

Specifications

IL10RA Chimeric
Recombinant Monoclonal
1 mg/mL
PBS with 0.02% ProClin 300
Q61727
Il10ra
This antibody was raised by immunising rats with the purified recombinant extracellular region of mouse Interleukin 10 Receptor.
200 μg
Primary
Mouse
Liquid
Flow Cytometry, Immunocytochemistry, Inhibition Assays
1B1.3a
Unconjugated
Il10ra
AW553859; CD210; CD210a; CDw210; CDW210A; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; HIL-10R; I10R; I10R1; il-10 receptor; il-10 receptor antagonist; IL-10 receptor subunit alpha; IL10R; IL-10R alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10R2; Il10ra; IL-10RA; interleukin 10 receptor subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha; mIL-10R
Rabbit
Affinity chromatography
RUO
16154
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
IgG κ
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