Invitrogen™ IL-6 Receptor Recombinant Rabbit Monoclonal Antibody (502), FITC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA552201

Product Code. 30019628

Description

Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Specifications

• Antigen: IL-6 Receptor
• Classification: Recombinant Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.5% BSA and 0.03% ProClin 300
• Gene Accession No.: P08887
• Gene Symbols: IL6R
• Immunogen: Recombinant Human IL-6R Protein (Leu 20-Pro365).
• Quantity: 25 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry
• Clone: 502
• Conjugate: FITC
• Gene: IL6R
• Gene Alias: CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3570
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid