IL-4 Monoclonal Antibody (OX81), Functional Grade, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-7045-050

Product Code. 17141462

Description

Description: This OX81 monoclonal antibody reacts with rat interleukin (IL)-4. Also known as BCDF, BCGF-1 and BSF-1, IL-4 is secreted by activated Th2 and natural killer T cells. This cytokine is also produced by Th1 and mast cells albeit to a lesser extent. IL-4 is species-specific and promotes proliferation and differentiation of B cells. IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of MHC class II and CD23. The OX81 antibody has been reported to exhibit neutralizing activity. Applications Reported: This OX81 antibody has been reported for use in intracellular staining followed by flow cytometric analysis, and western blotting. Applications Tested: This OX81 antibody has been tested by intracellular flow cytometric analysis of activated rat splenocytes. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.

IL-4 Monoclonal antibody specifically detects IL-4 in Rat samples. It is validated for Flow Cytometry, Functional Assay, Western Blot

Specifications

• Antigen: IL-4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: P20096
• Host Species: Mouse
• Quantity: 50 mg
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Functional Assay, Western Blot
• Clone: OX81
• Conjugate: Functional Grade
• Gene: Il4
• Gene Alias: B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; Binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 287287
• Content And Storage: 4° C
• Form: Liquid