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IL-38, clone: H127C, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-7385-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15547476

  • £186.69 / 100µg


EU Stock 1
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Description

Description

Description: The monoclonal antibody H127C recognizes human IL-38. IL-38 is a member of the Interleukin-1 family (IL-1F) and shares homology with IL-1R antagonist (IL-1Ra) and IL-36R antagonist (IL-36Ra). IL-38 is expressed mostly in the skin and proliferating B cells of the tonsil and is also present at low levels in the heart and placenta. IL-38 functions as an anti-inflammatory cytokine that inhibits IL-36 by binding to IL-36R and also inhibits the production of IL-17 and IL-22. Gene polymorphisms of IL-38 are associated with psoriatic arthritis, ankylosing spondylitis, and heart disease.Applications Reported: This H127C antibody has been reported for use in flow cytometric analysis, immunoprecipitation, western blotting, ELISA, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This H127C antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 0.1 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-38
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q8WWZ1
IL-38, FKSG75, IL1HY2, IL-1HY2, IL1-theta, FIL1-theta, FIL1T, IL38, UNQ6119/PRO20041, Interleukin-1 family member 10, Family of interleukin 1-theta, IL-1F10
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISAþFlow CytometryþImmunohistochemistryþImmunohistochemistryþImmunoprecipitationþWestern Blot
H127C
Unconjugated
IL1F10
Purified
IL1F10
IgG2b, kappa
100μg
Store at 2-8°C.
Primary
84639
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