IL-38 Mouse anti-Human, Clone: H127C, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-7385-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15547476

Quantity Price
1 £ 180.2 / 100µg
EU Stock 2
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Description and Specification

Specification

Applications Enzyme Linked Immunosorbent Assay
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Mouse
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2b
Primary or Secondary Primary
Antigen IL-38
Clone H127C
Species Reactivity Human
Conjugate Unlabeled
Gene Alias Interleukin-38, IL-1F10
Concentration 0.5mg/mL
Quantity 100μg
Format Purified

The monoclonal antibody H127C recognizes human IL-38. IL-38 is a member of the Interleukin-1 family (IL-1F) and shares homology with IL-1R antagonist (IL-1Ra) and IL-36R antagonist (IL-36Ra). IL-38 is expressed mostly in the skin and proliferating B cells of the tonsil and is also present at low levels in the heart and placenta. IL-38 functions as an anti-inflammatory cytokine that inhibits IL-36 by binding to IL-36R and also inhibits the production of IL-17 and IL-22. Gene polymorphisms of IL-38 are associated with psoriatic arthritis, ankylosing spondylitis, and heart disease.