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Invitrogen™ IL-34 Polyclonal Antibody

Product Code. 12848762
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Quantity:
100 μg
Unit Size:
100µg
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12848762 100 μg 100µg
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Product Code. 12848762 Supplier Invitrogen™ Supplier No. PA520585

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Description

Rabbit Polyclonal Antibody

Despite its predicted molecular weight, IL-34 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is human brain tissue lysate. PA5-20585 can be used with blocking peptide PEP-0705.

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-34
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Il34
Gene Accession No. Q4KM46, Q6ZMJ4, Q8R1R4
Gene Alias 2010004A03Rik; AI593503; C16orf77; IL34; IL-34; ILN; Interleukin; interleukin 34; Interleukin34; interleukin-34
Gene Symbols Il34
Host Species Rabbit
Immunogen A 16 amino acid peptide from near the amino terminus of human IL-34.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 146433, 498951, 76527
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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