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Invitrogen™ IL-34 Polyclonal Antibody

Product Code. 12808772
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Quantity:
100 μg
Unit Size:
100µg
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12808772 100 μg 100µg
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Product Code. 12808772 Supplier Invitrogen™ Supplier No. PA520594

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Description

Rabbit Polyclonal Antibody

Despite its predicted molecular weight, IL-34 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is human brain tissue lysate. PA5-20594 can be used with blocking peptide PEP-0714.

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-34
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Il34
Gene Accession No. Q4KM46, Q6ZMJ4, Q8R1R4
Gene Alias 2010004A03Rik; AI593503; C16orf77; IL34; IL-34; ILN; Interleukin; interleukin 34; Interleukin34; interleukin-34
Gene Symbols Il34
Host Species Rabbit
Immunogen A 13 amino acid peptide from near the center of human IL-34.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 146433, 498951, 76527
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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