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IL-33R (ST2) Rat anti-Mouse, PerCP-eFluor 710, Clone: RMST2-2, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-9335-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15529416

  • £83.43 / 25µg


EU Stock 5
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Disclaimers:

For Research Use Only.


Description

Description

The RMST2-2 monoclonal antibody reacts with ST2, also known as IL-33 receptor (IL-33R) or interleukin 1 receptor-like 1. ST2 is a member of the IL-1 receptor family. In the membrane-bound form, it consists of three extra-cellular immunoglobulin domains and an intracellular toll-interleukin-1 receptor domain. ST2 forms a dimer with IL-1R accessory protein in a ligand-dependent manner. The IL-33/ST2 interaction induces the production of TH2 cytokines. ST2 also has a soluble isoform lacking transmembrane and intracellular toll-interleukin-1 receptor domains. It is believed that the soluble form functions as a decoy receptor that can block membrane bound IL-33/ST2 interaction. ST2 is expressed by TH2 lymphocytes, mast cells, eosinophils, basophils, innate lymphocytes, smooth muscle cells, and endothelial cells and is involved in host defense, allergy, and inflammation. The IL-33/ST2 interaction has also been shown to be atheroprotective.
Specifications

Specifications

IL-33R (ST2)
RMST2-2
PerCP-eFluor 710
Conjugated
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
IL-1RL1, IL-1R4, T1
IgG2a
RUO
Primary
Murine