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Invitrogen™ IL-32 Polyclonal Antibody

Product Code. 16322635
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Quantity:
100 μL
Unit Size:
100µL
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16322635 100 μL 100µL
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Product Code. 16322635 Supplier Invitrogen™ Supplier No. PA585700

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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Positive Control: NCI-H929. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-a, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN-gamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-32
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene IL32
Gene Accession No. P24001
Gene Alias IL32; IL-32; IL-32alpha; IL-32beta; IL-32delta; IL-32gamma; ILN; Interleukin; interleukin 32; interleukin-32; interleukin-32 eta; interleukin-32 small; interleukin-32 theta; natural killer cell transcript 4; natural killer cells protein 4; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; Tumor necrosis factor alpha-inducing factor
Gene Symbols IL32
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human IL32. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9235
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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