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IL-32 Monoclonal Antibody (2I2), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA549250
This item is not returnable.
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Description
Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-a, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN-gamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.
Specifications
| IL-32 | |
| Monoclonal | |
| 500 μg/mL | |
| PBS with 4MG trehalose and 0.05MG sodium azide | |
| P24001 | |
| IL32 | |
| E. coli-derived human IL32 recombinant protein (Position: A31-K234). | |
| 100 μg | |
| Primary | |
| Human | |
| Lyophilized |
| ELISA | |
| 2I2 | |
| Unconjugated | |
| IL32 | |
| IL32; IL-32; IL-32alpha; IL-32beta; IL-32delta; IL-32gamma; ILN; Interleukin; interleukin 32; interleukin-32; interleukin-32 eta; interleukin-32 small; interleukin-32 theta; natural killer cell transcript 4; natural killer cells protein 4; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; Tumor necrosis factor alpha-inducing factor | |
| Mouse | |
| Antigen affinity chromatography | |
| RUO | |
| 9235 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| IgG2b |