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IL-25R (IL-17RB) Monoclonal Antibody (MUNC33), eFluor™ 660, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 50-7361-80
Code : NEW
Additional Details : Weight : 0.09500kg
Description
Description: This MUNC33 monoclonal antibody reacts with mouse interleukin-25 receptor (IL-25R), also known as IL-17RB. IL-25R is a 55 kDa transmembrane protein that dimerizes with IL-17RA to form the functional receptor for IL-25 (IL-17E). IL-25R is detectable in various tissues, including the lung and gastrointestinal tract and exists as both membrane bound and soluble form. IL-25/IL-25R interaction has been shown to activate the NF-kB, MAPK, and JNK pathways as well as gene transcription by STAT6, GATA-3, and NFATc1. IL-25R signals in T helper 2 (Th2) cells, type 2 innate lymphoid (ILC2) cells and some iNKT cells to promote differentiation and effector function. Whereas IL-25-deficient mice have an impaired Th2 response to parasitic helminth infection, elevated expression of IL-25 and IL-25R is observed in patients with chronic asthma and atopic dermatitis. Applications Reported: This MUNC33 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MUNC33 antibody has been tested by flow cytometirc analysis of mouse lymph node cells or IL-25R-transfected cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
IL-25R (IL-17RB) Monoclonal antibody specifically detects IL-25R (IL-17RB) in Mouse samples. It is validated for Flow Cytometry.Specifications
IL-25R (IL-17RB) | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
Q9JIP3 | |
IL17RB | |
IL-17RB Fc fusion protein | |
25 μg | |
Primary | |
Mouse | |
Antibody | |
IgG2a κ |
Flow Cytometry | |
MUNC33 | |
eFluor 660 | |
IL17RB | |
CRL4; cytokine receptor CRL4; cytokine receptor-like 4; ecotropic viral integration site 27; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL17BR; IL-17ER; Il17rb; IL-17RB; IL17RH1; IL-17Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7 | |
Rat | |
Affinity chromatography | |
RUO | |
50905 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
For Research Use Only.