Invitrogen™ IL-19 Monoclonal Antibody (350105)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA524093

Product Code. 15563782

Description

In direct ELISAs and Western blots, no cross-reactivity with recombinant humanIL-19 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.

Specifications

• Antigen: IL-19
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8CJ70
• Gene Symbols: IL19
• Immunogen: E. coli-derived recombinant mouse IL-19 Leu25-Ala176.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Western Blot
• Clone: 350105
• Conjugate: Unconjugated
• Gene: IL19
• Gene Alias: il 19; IL-10C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG.1; ZMDA1
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 329244
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized