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IL-17F Rat anti-Human, PE-Cy7, Clone: SHLR17, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 25-7169-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15548636

  • £78.88 / 25 tests


Estimated Shipment date
from Supplier 31-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The SHLR17 monoclonal antibody reacts with human interleukin (IL)-17F. IL-17F is a homodimeric, 34kDa member of the IL-17 family, which includes IL-17(A), B, C, D, E (IL-25). Within this family, IL-17A and IL-17F are produced preferentially by T helper 17 (Th17) cells, with other members produced more widely. IL-17F and IL-17A have many overlapping functions, but knockout studies have shown each to have independent functions as well. \i{In vitro\i} cultured Th17 cells have been shown to express IL-17F and IL-17A homodimers and IL-17A/F heterodimers depending on the culture conditions and their differentiation state. A heterodimer of IL-17RA and IL-17RC has been shown to bind IL-17F, resulting in target cell-secretion of pro-inflammatory cytokines and chemokines, as well as neutrophil recruitment.
Description & Specifications

Specifications

IL-17F
SHLR17
PE-Cy7
Conjugated
Rat
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-17F
IgG1
RUO
Primary
Human