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IL-17F Rat anti-Human, PE, Clone: SHLR17, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-7169-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15527106

  • £201.16 / 100 tests


EU Stock 3
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Disclaimers:

For Research Use Only.


Description

Description

The SHLR17 monoclonal antibody reacts with human interleukin (IL)-17F. IL-17F is a homodimeric, 34kDa member of the IL-17 family, which includes IL-17(A), B, C, D, E (IL-25). Within this family, IL-17A and IL-17F are produced preferentially by T helper 17 (Th17) cells, with other members produced more widely. IL-17F and IL-17A have many overlapping functions, but knockout studies have shown each to have independent functions as well. In vitro cultured Th17 cells have been shown to express IL-17F and IL-17A homodimers and IL-17A/F heterodimers depending on the culture conditions and their differentiation state. A heterodimer of IL-17RA and IL-17RC has been shown to bind IL-17F, resulting in target cell-secretion of pro-inflammatory cytokines and chemokines, as well as neutrophil recruitment.
Specifications

Specifications

IL-17F
SHLR17
PE
Conjugated
Rat
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.5μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-17F
IgG1
RUO
Primary
Human
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