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IL-17AF Rat anti-Mouse, PE, Clone: B8KN8R, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9171-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15597176

  • £246.00 / 100µg

Estimated Shipment
19-11-2020

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Description

Description

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several ""framework"" genes are found in all haplotypes. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Specifications

Specifications

IL-17AF
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q7TNI7, Q62386
Il17a, IL17F, Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17A, CTLA8, IL17, Interleukin-17F, IL-17F, Cytokine ML-1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
B8KN8R
PE
Il17f
Liquid
Il17a, Il17f
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
16171, 257630
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SDS
Documents

For Research Use Only.