Invitrogen™ IL-16 Monoclonal Antibody (14.1), Biotin

Mouse Monoclonal Antibody

Brand:  Invitrogen™ M161B

Product Code. 11844261

Description

M161B targets IL-16 in ELISA, and WB applications and shows reactivity with Human samples. The M161B immunogen is recombinant human IL-16. M161B detects IL-16 which has a predicted molecular weight of approximately 142 kDa. The M161B IL16 antibody (biotinylated conjugate of clone 14.1) has successfully been paired as the detection antibody in a sandwich ELISA with capture antibody M160E (clone 17.1) Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125 - 0.25 μg/mL for detection. Biotinylated antibody M161B (clone 14.1) and antibody M160E (clone 17.1) have successfully been used in combination with recombinant IL16 protein SIL16 in ELISA applications.

The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: IL-16
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 4% BSA and Proprietary preservative
• Gene Accession No.: Q14005
• Gene Symbols: IL16
• Immunogen: Recombinant human IL-16.
• Quantity: 250 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 14.1
• Conjugate: Biotin
• Gene: IL16
• Gene Alias: FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; Il16; IL-16; ILN; Interleukin; interleukin 16; Interleukin16; Interleukin-16; LCF; Lymphocyte chemoattractant factor; M-IL-16; mKIAA4048; neuronal interleukin 16; NIL16; PRIL16; prIL-16; prointerleukin 16; Pro-interleukin-16
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3603
• Content And Storage: -20°C
• Form: Liquid