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IL-13 Rat anti-Mouse, Biotin, Clone: eBio1316H, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-7135-85

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15380040

  • £170.59 / 500µg


Estimated Shipment date
from Supplier 30-06-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The eBio1316H antibody reacts with mouse IL-13. The eBio1316H antibody is a neutralizing antibody. Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4; this relates to a requirement for IL-4Ralpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.
Description & Specifications

Specifications

IL-13
eBio1316H
Biotin
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
500μg
Store at 2-8°C. Do not freeze.
Monoclonal
ELISPOT Detection Antibody
0.5mg/mL
Conjugated
Interleukin-13
IgG1
RUO
Primary
Murine