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IL-13, Biotin, clone: eBio1316H, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-7135-85

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15380040

  • £176.05 / 500µg


EU Stock 1
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Description

Description

Description: The eBio1316H antibody reacts with mouse IL-13. The eBio1316H antibody is a neutralizing antibody. Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4; this relates to a requirement for IL-4Ralpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.Applications Reported: The eBio1316H antibody has been reported useful for neutralization, ELISA detection, and ELISPOT detection.Applications Tested: The biotinylated eBio1316H antibody has been tested as the detection antibody in a sandwich ELISA (and ELISPOT assay) for analysis of mouse interleukin-13 (IL-13) in combination with the purified eBio13A (14-7133) antibody for capture and recombinant mouse IL-13 (14-8131) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.25-1 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate. For intracellular staining of mouse IL-13, the fluorochrome labelled eBio13A antibody is recommended.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-13
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P20109
Interleukin-13, ALRH antibody, NC30 antibody, P600 antibody
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
ELISA
eBio1316H
Biotin
Il13
Conjugated
Il13
IgG1, kappa
500μg
Store at 2-8°C. Do not freeze.
Primary
16163
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