IL-12/IL-23 Rat anti-Mouse, eFluor 660, Clone: C17.8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-7123-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15391940

Quantity Price
1 £ 213.39 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
Add to basket


Description and Specification

Specification

Isotype IgG2a
Applications Flow Cytometry (Intracellular Staining)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100μg
Host Species Rat
Clone C17.8
Gene Alias Interleukin-12, IL12 / Interleukin-23, IL23 p40
Regulatory Status RUO
Antigen IL-12/IL-23
Conjugate eFluor 660
Primary or Secondary Primary
Format Conjugated
Concentration 0.2mg/mL

The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.