IL-12/IL-23 p40 Monoclonal Antibody (C17.8), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-7123-050

Product Code. 17161482

Description

The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70 kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.

IL-12/IL-23 p40 Monoclonal antibody specifically detects IL-12/IL-23 p40 in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Immunoprecipitation, Neutralization, Western Blot

Specifications

• Antigen: IL-12/IL-23 p40
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: P43432, Q9EQ14
• Host Species: Rat
• Quantity: 50 mg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Functional Assay, Immunoprecipitation, Neutralization, Western Blot
• Clone: C17.8
• Conjugate: Functional Grade
• Gene: Il23a
• Gene Alias: CLMF; CLMF p40; CLMF2; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12/IL 23p40; il 23; IL 23 p40; Il12; IL-12 subunit p40; IL12, subunit p40; IL12B; IL-12B; IL12p40; Il-12p40; il23; IL-23; IL23 p41; IL-23 subunit alpha; Il23a; IL-23A; IL-23-A; IL23P19; IL-23p19; ILN; IMD28; IMD29; Interleukin; Interleukin 12; interleukin 12 40 kDa subunit; interleukin 12 40kDa subunit; interleukin 12, p40; interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin 23 p19 subunit; interleukin 23 subunit alpha; Interleukin 23, alpha subunit p19; Interleukin12; interleukin-12 beta chain; interleukin-12 p40; interleukin-12 p40 subunit; interleukin-12 subunit beta; interleukin-23 p19 subunit; interleukin-23 p40 subunit; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; natural killer cell stimulatory factor, 40 kD subunit; NK cell stimulatory factor chain 2; NKSF; NKSF2; p19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16160, 83430
• Content And Storage: 4° C
• Form: Liquid