Learn More
Eurofins DiscoverX IKKβ Protein, Active
Description
Nuclear factor kappa B (NF-kB) plays a critical role in the inducible expression of a large number of genes involved in immune, inflammatory and apoptotic processes. NF-kB is associated with IkB in cytoplasm, which inhibits NF-kB activity. IkB kinase (IKK), which consists of at least three proteins (IKK-1/a, IKK-2/b, and IKK-3/g), phosphorylates IkB and mediates IkB degradation. Once IkB is removed, NF-kB is free to enter the nucleus of the cell and transcriptionally activate its targeted genes.
GenBank AF080158
Specifications
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molecular Weight (g/mol) | 87.6 kDa |
| Quantity | 10 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Full-length |
| Purity or Quality Grade | ≥43% |
| Protein | IKKβ, active |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.