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Invitrogen™ IKK alpha Polyclonal Antibody
Description
In Western blot applications, this antibody detects a band at ~85kDa. A suggested positive control is Hela cell lysate. PA5-19914 can be used with blocking peptide PEP-0040.
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex. IKK alpha along with IKK beta and a regulatory protein NEMO (IKK gamma) phosphorylates IkB proteins which targets the later for ubiquitin mediated degradation. It is involved with several cellular processes with extensive studies on its role in inflammation and cell survival.
Specifications
Specifications
| Antigen | IKK alpha |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | CHUK |
| Gene Accession No. | O15111 |
| Gene Alias | AI256658; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; FLJ40509; I kappa B kinase 1; i kappa-B kinase alpha; ikappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; IkB kinase alpha subunit; IkB kinase-alpha; ikBKA; IKBKB; IKK alpha; IKK1; IKK2; Ikka; IKK-A; IKK-a kinase; IKK-alpha; IKKB; IKK-B; IKK-beta; Inhibitor of nuclear factor kappa-B kinase subunit alpha; kinase beta; MGC131801; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase alpha; TCF16; TCF-16; Transcription factor 16 |
| Gene Symbols | CHUK |
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