Invitrogen™ IGFBP7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588924

Product Code. 16576991

Description

Immunogen sequence: SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL; Positive Samples: Mouse kidney, Rat kidney.

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.

Specifications

• Antigen: IGFBP7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IGFBP7
• Gene Alias: AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 289560, 29817
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q61581
• Gene Symbols: IGFBP7
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 27-282 of human IGFBP7 (NP_0015441).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG