Invitrogen™ IGFBP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529741

Product Code. 13414007

Description

Recommended positive controls: NT2D1. Predicted reactivity: Mouse (94%), Rat (95%), Pig (100%), Sheep (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Specifications

• Antigen: IGFBP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IGFBP2
• Gene Alias: AI255832; BP2; BRL-BP; IBP2; IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP2; IGFBP-2; IGF-BP53; ILGFBPA; Insulin like growth factor binding protein; insulin like growth factor binding protein 2; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; insulin-like growth factor-binding protein 2; mIGFBP-2; OTTHUMP00000207753
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3485
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.77 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P18065
• Gene Symbols: IGFBP2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human IGFBP2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG