Invitrogen™ IGF2BP2 Recombinant Rabbit Monoclonal Antibody (1H13L3)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ 703102

Product Code. 16311754

Description

This antibody is predicted to react with Monkey, Pig, Bovine. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.

Specifications

• Antigen: IGF2BP2
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q9Y6M1
• Gene Symbols: IGF2BP2
• Immunogen: Peptides corresponding to human IGF2BP2 [1) aa17-aa32 2) aa583-aa599].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry
• Clone: 1H13L3
• Conjugate: Unconjugated
• Gene: IGF2BP2
• Gene Alias: C330012H03Rik; Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF2BP2; IGF-II mRNA-binding protein 2; Imp2; IMP-2; insulin like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; Neilsen; p62; RGD1305614; VICKZ family member 2; VICKZ2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10644
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid