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Description
Immunogen sequence: ASPSAGFPMD FNVTLRLRAE LGALHSAWVT MPWFQHYRNV TVGPPENIEV TPGEGSLIIR FSSPFDIADT STAFFCYYVH YWEKGGIQQV KGPFRSNSIS LDNLKPSRVY CLQVQAQLLW NKSNIFRVGH LSNIS Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 57%.
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
Specifications
Specifications
| Antigen | IFNGR2 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | IFNGR2 |
| Gene Accession No. | P38484 |
| Gene Alias | AF-1; Ifgr2; Ifgt; IFN-gamma receptor 2; IFN-gamma-R2; IFN-gamma-R-beta; IFNGR2; IFNGT1; IMD28; Interferon gamma receptor 2; interferon gamma receptor 2 (interferon gamma transducer 1); interferon gamma receptor accessory factor 1; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; Interferon gamma receptor beta-chain; Interferon gamma transducer 1 |
| Gene Symbols | IFNGR2 |
| Show More |
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